This paper proposes different robust and low-complexity space time codes which provide more reliability for industrial automation. An innovative synchronized uplink system configuration for an Industrial Environment is proposed. Mathematical framework for estimating the channel phase of each Slave Node (SN) is developed. Furthermore, the channel is practically estimated based on an innovative method using parallel sequence spread spectrum (PSSS) implemented in Universal Software Radio Peripheral (USRP). The proposed space time codes are applied in the uplink of an industrial communication system where the channel is modelled using Quasi Deterministic Radio Channel Generator (Quadriga) which follows a geometry-based stochastic approach. Simulation results exposed that the proposed codes surpass Alamouti code for Industrial Automation. The bit error rate (BER) performance demonstrates that the achieved coding gain for the proposed codes is higher than Alamouti code leading to more robust communication. Furthermore, a low complexity decoders based on minimum mean squared error (MMSE) and zero forcing (ZF) algorithms are designed at the receiver side. The proposed codes give a predominant execution against the state-of-the-art space time codes for Industry 4.0.