Wireless communication is the most effective communication to convey audio or video information among the population. It enables the masses to connect throughout the world. Wireless technologies improve the lifestyle of individuals in rural and poor communication areas. In this view, the quality of a reliable signal can be enhanced by minimizing carrier interference. In this paper bit error rate of an image, signal is transmitted over fading channel is analyzed using orthogonal frequency multiplexing and channel estimation technique. An Orthogonal Frequency Multiplexing (OFDM) provides prominent bandwidth effectiveness and improved immunity to the fading environments. In OFDM, the data is modulated using multiple numbers of subcarriers that are orthogonal to each other. A cyclic prefix is infixed between OFDM symbols to annihilate the inter symbol interference (ISI) and inter-carrier interference (ICI). The least square channel estimation method is used to minimize the effect of multipath fading. An image, signal is modulated using BPSK, QPSK, 16QAM and 64QAM digital modulation schemes with OFDM and channel estimation and transmitted over AWGN and fading channel.